Abstract: This study focused on the reform and practice of blended online and offline teaching of genetics using online open course alliance platform for universities in the Guangdong-Hong Kong-Macao Greater Bay Area (referred to as the “alliance platform”). By using the “alliance platform”, diversified teaching activities, such as in-depth discussions around course teaching themes, MOOC video learning, and post-class exercises and quizzes, have been promoted. This approach facilitated efficient management and supervision of students’ daily learning within the course. The practice of teaching reform has shown that blended online and offline teaching management based on the “alliance platform” significantly improves students’ learning efficiency, teamwork awareness and ability, greatly mobilizes their learning initiative and positivity, and stimulates their learning enthusiasm. The findings of this study not only suggested new approaches to enhancing the quality of genetics teaching, but also offered practical insights and references for implementing blended online and offline teaching in other courses.

Key words: alliance platform, genetics, blended online and offline teaching, teaching design, teaching effect