Abstract: Considering the abundance ofDrosophilaspecies and their ease of collection/culture, a serial experiment on genetic diversity was designed usingDrosophilaflies as experimental materials. These experiments integrated and extended the established experimental system. The experimental series comprised 5 components: observation, collection, and culture ofDrosophila, species identification via DNA barcoding, creation and observation of salivary gland chromosome specimens, isozyme analysis, and SSR analysis. These experiments collectively assessed the genetic diversity ofDrosophilaat the phenotypical, chromosome, protein, and DNA levels. This multi-tiered approach featured progressive and exploratory characteristics. Using consistent experimental samples throughout the series enables students to systematically understand the knowledge and technology of genetics and comprehensively improve their experiment capabilities.

Key words: genetic diversity, genetics, experiment teaching;Drosophila, comprehensive experiment