Abstract: The research progress on the functions of actin in virus entry, replication, release and spread between the cells was summarized, which focused on the specific process and function of virus recruitment and induction of actin formation in different stages of virus infection as well as the molecular mechanism of virus regulating actin rearrangement. Although much is known about the involvement of actin in virus entry and release, there is still less research on its involvement in virus replication and assembly. The molecular mechanism and signal pathway of virus regulating actin need to be further studied in order to clarify the molecular mechanism of virus infection and develop new antiviral strategies.

Key words: actin, virus, infection, cytoskeleton