Abstract: Through the transformation of excellent scientific research projects and cooperation with high-tech enterprises, Virtual Simulation Experiment Teaching Center for Biological Science and Technology built a batch of high-quality virtual simulation experiment teaching resources. The multi-level and diversified resources provide a favorable environment for students to learn frontier scientific knowledge, comprehensive scientific research training, and biological downstream industry technology training, at the same time，they realize the learning and extension of interdisciplinary knowledge, and reform the teaching modes effectively. The 24/7 open and shared virtual simulation experimental teaching platform achieves the organic integration of online teaching resources such as virtual simulation experimental teaching software, standardized experimental videos, teaching courseware and test question banks, meets the needs of experimental teaching anytime and anywhere, and supports a series of mixed online and offline experimental teaching courses. The center, in collaboration with National Demonstration Center for Experimental Biology Education, forms a "dual center" integrated development of innovative talent training experimental teaching system. The experimental teaching mode of "combining virtuality and reality" improves the comprehensive scientific research ability of students and the professional level of teachers, and cultivates the practical talents of biotechnology innovation to meet the needs of society.

Key words: virtual simulation experiment, experimental teaching resources, shared platform, combining virtuality and reality, cultivation of talent