Abstract: The experimental project of "searching for others-application of nucleic acid detection" was summarized here, and the discussion of practical experience of applying part of the research project to the undergraduate general education course was performed. In this experiment project, the Arabidopsis thaliana T-DNA insertion mutants were used as materials to explore the application of nucleic acid detection technology in scientific research and medical testing through genomic DNA extraction, PCR detection and band analysis, covering a complete scientific research process. The practice of this experiment enables non-biology majors to understand the implementation process of biology scientific research projects while acquiring knowledge in biology and experimental skill points related to nucleic acid extraction in biology. It encourages students to think about the background, process and significance of the development of technical means in the nucleic acid testing, cultivating dispersive thinking, innovation and practice ability of students, and laying the foundation for the cultivation of comprehensive and innovative talents in the new era.

Key words: transformation of scientific research project, general education course, experimental teaching, nucleic acid test