Abstract: Pathogenic biology and immunology is one of the important basic courses of medicine. Based on the characteristics of the course and the learning situation of college students, some reforms and explorations have been carried out on the experimental teaching, including making reasonable teaching plan, integrating basic experiments, increasing comprehensive experiments, embedding comprehensive ability training, and optimizing the evaluation modes, in order to improve the students′ learning enthusiasm and comprehensive quality, and elevate the teaching quality and effect.

Key words: pathogenic biology and immunology, experimental teaching, reform