Abstract: Using "the central dogma" as a main stream, five domains of structure and function of DNA, RNA and protein, DNA replication, damage repair and transposition, transcription control, translation regulation, synthetic biology and molecular operation are designed for teaching of molecular biology. A scientific-story-directed teaching mode where the theories can be discussed through telling stories behind the discoveries has been practiced. The story-directed teaching mode is found to be good for students to learn the biological theories and methods in an interesting and easy way, to understand the logic and reasoning behind the theories as well.

Key words: molecular biology, the central dogma, scientific stories, teaching