Abstract: In recent years, we have explored the pilot reform of Nobel Prize cases as a main clue to guide the course of “Molecules and Cells”. We selected 15 award cases covering 11 core chapters of the course, each of which was jointly investigated by two students. The students are recommended to use the ceremony report of Nobel Prize winner as a blueprint, focusing on the research background, the highlights of discoveries/inventions, and the theoretical or applied values by the scientists. In the in-class practice, a standard unit of introduction-report-discussion-summary is constructed, using the method of panel discussion to improve teaching effectiveness. The strategy integrates our national needs, science and art, facing challenges, and innovative spirit. This plan has stimulated students’ enthusiasm for self-directed learning, cultivated students’ basic biomedical qualities and concepts through extracurricular research and in-class discussions. This reform has achieved beneficial performances under limited course time and 90% students have achieved significant results after course learning. Through teaching practice, we have further proposed improvement ideas such as method optimization, viewpoint update, ideological and political integration, and perspective enhancement, which has potential reference significance for the teaching reform of life foundation courses in biomedical majors.

Key words: molecules and cells, Nobel Prize, teaching innovation, biomedicine