Abstract: The traditional curriculum practice teaching mode is teacher centered, and most of the practice sessions are mainly based on verification and visiting, students’ experience and driving force for understanding and mastering knowledge points, operation points and experimental methods were insufficient. And, it cannot meet the training requirements of students with innovative thinking and ability. Therefore, the practice teaching of this course has been reformed. In the teaching process, the multi-level practice teaching method oriented by innovation and entrepreneurship was adopted, which embodied the concept of student-centered cultivation and integrated innovation and entrepreneurship education into professional practice teaching. We realized the organic integration of the first classroom and the second classroom, improved the students’ learning effect, and drove the students’ creation and innovation passion using this teaching mode.

Key words: creation and innovation education, orientation, multiple teaching, metabolic control fermentation, practical courses
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