Abstract: In the process of cultivating undergraduate students in universities, a very significant purpose is to improve students′ scientific research and innovation ability and to realize the cultivation of all-round talents. The cultivation of practical operation ability is an important part of the practical teaching of undergraduates. However, a considerable number of colleges and universities currently are facing the problems such as the large number of students, limited experimental hours, and lack of practical opportunities. In view of the problems above, combined with the "strive to improve the whole staff, the whole process and the all-round education system" put forward by our Institute, this paper explicited the implementation scheme of the laboratory rotation tutor system in the cultivation of undergraduate students majoring in biology，and determined the cycle and requirements of the laboratory rotation, improved the experimental content of the laboratory rotation, and established the evaluation method of the system. After more than two years′ practice, it showed that the system made full use of students′ initiative, helped students to choose their favorite research direction, trained students′ comprehensive quality and creative thinking of scientific research and further improved the quality of undergraduate practice teaching.

Key words: laboratory rotation tutor system, undergraduate, all-round, practice teaching