Abstract: Gamma-aminobutyric acid (GABA) is a free-state, non-protein amino acid that is widely distributed in nervous tissues and peripheral tissues. It has various physiological functions such as brain-enhancement, analgesia, and hypnosis. Studies have shown that GABA also affects the reproductive function through the hypothalamus-pituitary-ovarian axis in female animal. The paper reviewed the role of GABA in reproductive endocrine, oocyte development and puberty, which provides a basis for further studying its effect on reproduction of female animal.

Key words: γ-aminobutyric acid, reproductive endocrine, oocyte, puberty