Abstract: Innovation is the driving force of scientific research. Innovation thinking is the necessary requirement of the cultivation of high-quality scientific research personal. According to graduate students showing low research interest, lacking innovation thinking, low scientific research quality during the process of graduate education and major feature of Microbiology and development direction of subject, the education of "Advanced Microbiology" performs reform. The course reform of young teachers, curriculum professionalization, diverse teaching, flexible examination and so on performs to train students′ innovation thinking, which will export high-level personnel with high research quality and strong comprehensive ability for development of Chinese science and technology.

Key words: advanced microbiology, innovation thinking, education reform