Abstract: Practical biostatistics, which is a branch of statistics that applies statistical methods to analyze biological data, emphasizes both theoretical frameworks and practical applications. In the big data era, where importance of data and data analysis is escalating, practical biostatistics has gained increasing attention. Serving as a basic course for students, it not only requires a clear explanation of the mathematical and statistical knowledge but also emphasizes its practicality, making it challenging to teach. Here, the design, content arrangement and teaching philosophy of the practical biostatistics course were discussed based on the teaching experiences, in order to serve as a reference for the lecture design of interdisciplinary course.

Key words: practical biostatistics, interdisciplinary, strengthening basic disciplines plan, bilingual education, innovative teaching