Abstract: The research trends and existing achievements in the neuroprotective field of domestic plant extracts were summarized from these aspects such as the causes of neuronal injury. The active substance components, the typical manifestations, the underlying mechanism, the research trend and application prospect of domestic plant extracts were prospected in order to provide some reference for the further researches.

Key words: plant extract, neuroprotection, oxidative stress, signal pathway, gene express, damage and apoptosis