Abstract: Dopamine is a widely distributed neurtransmitter in the brain. A variety of neuropsychiatric disorders are associated with dopamine system dysfunction. Since many Drosophila melanogaster genes that involve in the synthesis, transport, excretion, metabolism and signal transduction of dopamine are conserved in human, fruit flies have been extensively used to study the regulation of dopamine signaling. Here, we review the recent researches related to dopamine and its regulation by stress in Drosophila melanogaster.

Key words: Drosophila melanogaster, dopamine, stress