Abstract: Plants have evolved sophisticated and fine-tuned regulatory mechanisms in response to various stresses. The NPR1 of salicylic acid (SA) receptor plays the essential role in plant innate immunity mediated by SA. In October 2018, the scientists have clarified the regulatory function and molecular mechanism of NPR1 in cold response in plant, and it was helpful to analyze the molecular network of precise controlling the responding of multi-stress.

Key words: NPR1, cold stress, salicylic acid, immune response