Abstract: tAlzheimer′s disease (AD), the most common form of dementia among the elderly, is characterized by the progressive decline of cognitive function. Increasing evidence indicates that the production, accumulation and aggregation of amyloid β (Aβ) are central to the pathogenesis of AD. Catechins are widespread in the plant kingdom and have been shown to exert neuroprotective activities in AD involving multimodal activities. The therapeutic strategies of catechins for AD targeting amyloid cascade hypothesis are reviewed and the main problems in the further research are discussed, aiming to providing some references for the study and application of catechins in AD.

Key words: Alzheimer′s disease, Aβ, catechins