Cadherin superfamily is a class of glycoproteins involved in cell-cell adhesion and cell-matrix interaction. Their regulating expression during development plays a crucial role in the morphogenesis and patterning of tissues and organs. It is known that N- -glycosylation is existed in cadherins. Besides that, the modification of O-mannosyaltion was found recently in these molecules. In this review, the recent progress of N-glycosylation and O-mannosylation of cadhesins was summarized.

cadherin, protein-glycosylation, glycosyltransferases, O-mannosylation