生物学杂志

生物学杂志 ›› 2019, Vol. 36 ›› Issue (5): 89-.doi: 10.3969/j.issn.2095-1736.2019.05.089

• 综述与专论 • 上一篇    下一篇

γ-氨基丁酸调控雌性动物生殖的研究进展

  

  1. 安徽农业大学 动物科技学院， 合肥 230036
  • 出版日期:2019-10-18 发布日期:2019-10-11
  • 通讯作者: 方富贵，教授，硕士生导师，研究方向为动物生殖调控机理与技术，E-mail：fgfang@163.com
  • 作者简介:司文宇，硕士研究生，研究方向为动物生殖调控机理与技术，E-mail:780575028@qq.com
  • 基金资助:
    国家自然科学基金资助项目（31472096）

Research progress of gamma-aminobutyric acid regulating female reproduction

  1. College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China
  • Online:2019-10-18 Published:2019-10-11

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摘要： γ-氨基丁酸（gamma-aminobutyric acid，GABA）是一种天然存在的非蛋白质氨基酸，以游离态广泛分布于神经组织和外周组织，具有健脑益智、镇痛、催眠等多种生理功能。研究表明GABA还通过下丘脑-垂体-卵巢轴来影响生殖功能。综述了GABA在生殖内分泌、卵母细胞发育和初情期等方面的作用，为进一步研究GABA对雌性生殖的影响提供依据。

关键词: font-size:medium, ">γ-氨基丁酸；生殖内分泌；卵母细胞；初情期

Abstract: Gamma-aminobutyric acid (GABA) is a free-state, non-protein amino acid that is widely distributed in nervous tissues and peripheral tissues. It has various physiological functions such as brain-enhancement, analgesia, and hypnosis. Studies have shown that GABA also affects the reproductive function through the hypothalamus-pituitary-ovarian axis in female animal. The paper reviewed the role of GABA in reproductive endocrine, oocyte development and puberty, which provides a basis for further studying its effect on reproduction of female animal.

Key words: γ-aminobutyric acid, reproductive endocrine, oocyte, puberty

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