Abstract: Currently, researchers apply mouse as the ideal model for human disease researches. Many, if not most of the research fruits, however, cannot be transferred to human clinical application due to huge species differences. On the other hand, ethic issues and difficulties on obtaining human materials barrier the way of doing direct research on human. These obstacles put non-human primates, which resembles with human the most, as a better model species than mouse for understanding human. The born of cloned monkeys “Zhongzhong” and “Huahua” by somatic cell nuclear transfer not only closure the wide range doubt on whether primate can be cloned, but set up a milestone for human disease researches.

Key words: non-human primates, somatic cell nuclear transfer, cloned monkeys