生物学杂志

生物学杂志

• 教学研究 • 上一篇    下一篇

大学生理学实验教学中新的骨骼肌收缩实验的创立

  

  1. 1. 西北大学 生命科学学院， 西安 710069； 2. 北京师范大学 燕化附中， 北京 102500
  • 出版日期:2019-06-18 发布日期:2019-06-18
  • 作者简介:王慧平，博士，讲师，研究方向为动物生理学，E-mail: wanghp@nwu.edu.cn
  • 基金资助:
    陕西省教育厅自然科学专项项目（14JK1755）；西北大学本科教育质量提升项目（动物生理学JX17129）；西北大学2018年省级级大学生创新实验项目

Establishing a new experiment on skeletal muscle contraction in experimental course of physiology

  1. 1. College of Life Sciences, Northwest University, Xi′an 710069; 2. Yanhua Middle School Affiliated to Beijing Normal University, Beijing 102500, China
  • Online:2019-06-18 Published:2019-06-18

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摘要： 结合自身科研方向，创立了新的骨骼肌收缩实验并应用于生理学实验教学。半游离模拟失重和正常大鼠后肢比目鱼肌，观察由不同形式电刺激诱发的收缩情况，并对比比目鱼肌肌重、收缩张力、收缩时程及柠檬酸合酶活性的差异，以反映骨骼肌收缩形式与电刺激的关系及模拟失重状态下骨骼肌发生的废用性萎缩。实验简单、易行、高效，不但可达到传统骨骼肌收缩实验的教学目的，还可让学生了解航天失重对人体生理健康的影响，激发学生的学习兴趣。

关键词: 生理学, 实验教学, 骨骼肌收缩, 新实验

Abstract: The purpose of this study was to establish a new experimental methodology on skeletal muscle contraction based on own scientific research, and develop it into the experimental course of physiology. The experiment was carried out on partly dissociating soleus of simulated weightlessness and normal rats, and electrical stimulation was used to induce soleus to contract. Additionally muscle mass, contraction force, contraction time course, and the activity of citrate synthase in soleus were compared. The presented results reveal that not only the relationship between the skeletal muscle contraction with electrical stimulation form, but also the disuse atrophy of skeletal muscle resulted from simulated weightlessness. The new experiment is easily verified, understood and executed. It can achieve the instructional objectives of conventional skeletal muscle contraction experiment. Furthermore, it provides a chance for university students to understand the basic concepts of human′s health in space and develop their learning interests.

Key words: physiology, experimental course, skeletal muscle contraction, new experiment

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