生物学杂志

生物学杂志 ›› 2023, Vol. 40 ›› Issue (6): 47-.doi: 10.3969/j.issn.2095-1736.2023.06.047

• 研究报告 • 上一篇    下一篇

C@TiCoO3 @TiO2 纳米材料制备及在可见光下的抗菌性

周　游， 章少琪， 李昀霏， 李　松， 甄德帅， 陈丽丽   

  1. 南华大学 衡阳医学院 公共卫生学院， 衡阳 421001
  • 出版日期:2023-12-18 发布日期:2023-12-18
  • 通讯作者: 陈丽丽，博士，教授，研究方向为卫生检验学，E-mail:chlili720612@163.com；甄德帅，博士，教授，研究方向为卫生检验学，E-mail:569264666@qq.com；陈丽丽与甄德帅为共同通信作者
  • 作者简介:周游，硕士研究生，研究方向为卫生检验学，E-mail:2495113696@qq.com
  • 基金资助:
    湖南省自然科学青年基金项目（2021JJ40454）；贵州省科技厅基础研究计划项目(黔科合基础-ZK\[2022\]一般 551)

The preparation of C@TiCoO3 @TiO2nanocomposites and#br# its antibacterial properties

ZHOU You, ZHANG Shaoqi, LI Yunfei, LI Song, ZHEN Deshuai, CHEN Lili   

  1. School of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, China
  • Online:2023-12-18 Published:2023-12-18

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摘要： 研究通过溶胶-凝胶法，将钴元素（Co）与TiO2掺杂在一起合成C@TiCoO3@TiO2纳米材料，并用扫描电子显微镜（SEM）、X射线衍射光谱（XRD）、X射线光电子能谱（XPS）和紫外-可见漫反射测试（UV-Vis DRS）对其进行表征。结果表明：该材料由Ti、O、C、Co元素组成，呈块状；主要以锐钛矿晶型形式存在，可见光的吸收范围大（762 nm），禁带宽度窄（1.63 eV），对可见光有较好的响应能力。5 mg/mL的C@TiCoO3@TiO2在LED可见光（功率7 W）下，分别照射60和100 min即可完全杀灭金黄色葡萄球菌和大肠埃希菌。细胞毒性实验表明，合成的C@TiCoO3@TiO2具有较好的生物相容性。实验合成的C@TiCoO3@TiO2纳米复合材料有潜在的抗菌应用价值。

关键词: font-size:9.00pt, line-height:150%, ">font-size:9.00pt, line-height:150%, ">Co掺杂TiO2；TiO2；光催化；可见光；抗菌活性

Abstract: Cobalt (Co) and TiO2 were doped together to synthesize C@TiCoO3@TiO2 by sol-gel method and then characterized by scanning electron microscopy (SEM), X-ray diffraction spectroscopy (XRD), X-ray photoelectron spectroscopy (XPS) and UV-Vis diffuse reflection spectroscopy (UV-Vis DRS). The results of SEM and XPS showed that the material was in bulk form and composed of Ti, O, C and Co elements. XRD mapping showed that C@TiCoO3@TiO2 existed mainly in the form of anatase crystals with a large specific surface area. The map of UV-Vis DRS showed that C@TiCoO3@TiO2 had a wide range of visible light absorption (762 nm), a narrow gap of band (1.63 eV) and a superior response to visible light. 5 mg/mL C@TiCoO3@TiO2 could completely kill Staphylococcus aureus and Escherichia coli under LED visible light irradiation (power 7 W) for 60 and 100 minutes, respectively. The cytotoxi-city test showed that the material had good biocompatibility. It showed that the C@TiCoO3@TiO2 nanocomposite had been successfully synthesized and would have potential value as an antimicrobial application.

Key words: cobalt-doped titanium dioxide, titanium dioxide, photocatalysis, visible light, antibacterial activity

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