生物学杂志

生物学杂志 ›› 2022, Vol. 39 ›› Issue (4): 88-.doi: 10.3969/j.issn.2095-1736.2022.04.088

• 综述与专论 • 上一篇    下一篇

基于硫巯基化的硫化氢信号分子作用新途径

  

  1. 云南师范大学 生命科学学院 生物能源持续开发利用教育部工程研究中心 
    云南省生物质能与环境生物技术重点实验室, 昆明 650500
  • 出版日期:2022-08-18 发布日期:2022-08-15
  • 通讯作者: 李忠光，教授，博士研究生导师，研究方向为植物逆境生物学，E-mail: zhong guang_li@163.com
  • 作者简介:李小二，硕士研究生，研究方向为植物逆境生物学，E-mail: xiaoer_li@163.com
  • 基金资助:
    国家自然科学基金项目(32160065, 31760069)

A novel way of action of hydrogen sulfide signal molecule based on S-sulfhydration in plants

  1. Key Laboratory of Biomass Energy and Environmental Biotechnology of Yunnan Province, Engineering Research
    Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, School of Life Sciences,
    Yunnan Normal University, Kunming 650500, China
  • Online:2022-08-18 Published:2022-08-15

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摘要： 描述植物中基于巯基的翻译后修饰蛋白质硫巯基化及其对靶蛋白的构象、活性、稳定性和亚细胞定位的改变和细胞代谢的调节，以及硫巯基化与其他翻译后修饰亚硝基化、次磺酰化、亚磺酰化、磺酰化和谷胱甘肽化的相互作用。分析植物中硫化氢(H2S)信号自我放大及对信号分子活性氧、一氧化氮、糖、脱落酸、乙烯和褪黑素的关键代谢酶和信号蛋白的硫巯基化修饰。总结植物中H2S信号通过对其代谢酶的硫巯基化修饰的自我放大及H2S通过硫巯基化与活性氧、一氧化氮、糖、脱落酸、乙烯和褪黑素信号的交互作用。展望H2S对其他植物激素生长素、赤霉素、细胞分裂素、油菜素内脂、茉莉酸、水杨酸和独脚金内酯的关键代谢酶和其他信号蛋白的硫巯基化修饰的效应。

关键词: 硫化氢, 一氧化氮, 植物激素, 蛋白质硫巯基化, 活性氧

Abstract: Sulfhydryl group-based posttranslational modification protein S-sulfhydration and its effect on the conformation, activity, stability, and cellular localization of target proteins and the regulation of cellular metabolism as well as the interaction of S-sulhydration with nitrosylation, sulfenylation, sulfinylation, sulfonylation, and glutathionylation in plants were described. In addition, the S-sulfhydration of hydrogen sulfide (H2S) on the key enzymes and signaling proteins involved in H2S, reactive oxygen species (ROS), nitric oxide (NO), sugar, abscisic acid, ethylene, and melatonin in plants was analyzed. Also, H2S signaling-self amplification by S-sulfhydration of its metabolic enzymes and the interaction between H2S and ROS, NO, sugar, abscisic acid, ethylene, melatonin signaling by protein S-sulfhydration in plants was concluded. The effect of H2S on the key metabolic enzymes and signaling proteins of the other plant hormones auxin, gibberelin, cytokinin, brassinosteroids, jasmonic aicd, salicylic aicd, and strigolactone by protein S-sulfhydration was prospected.

Key words: hydrogen sulfide, nitric oxide, plant hormone, protein S-sulfhydration, reactive oxygen species

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