生物学杂志

生物学杂志

• 综述与专论 • 上一篇    下一篇

胃蛋白酶的分离现状及其活性研究进展

  

  1. 中国海洋大学 食品科学与工程学院， 青岛 266003
  • 出版日期:2016-06-18 发布日期:2016-06-18
  • 通讯作者: 梁兴国，教授，研究方向为核酸化学与生物技术，E-mail: liangxg@ouc.edu.cn
  • 作者简介:刘宇，博士研究生，研究方向为食品化学与营养支持，E-mail: shishui87@163.com
  • 基金资助:
    国家自然科学基金（31201327）；国家教育部留学回国人员科研启动基金资助项目；国家青年千人计划（National Youth Qianren Plan）；山东省自然科学基金杰出青年基金（JQ201204）

The research progress in pepsin purification and enzymatic activity#br#

  1. College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China
  • Online:2016-06-18 Published:2016-06-18

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摘要：

阐述了胃蛋白酶的结构及性质，总结了哺乳动物和鱼类胃蛋白酶的分离进展，并比较分析了不同物种间胃蛋白酶的性质和特点；同时对胃蛋白酶新发现的降解糖类和核酸类物质的新活性进行了总结分析。胃蛋白酶作为生物体内重要的消化酶，其具有蛋白酶、糖酶和核酸酶活性，是一种“多功能酶”，将为胃蛋白酶进一步研究以及应用提供一定参考。

关键词: 胃蛋白酶, 酶系组成, 新活性, 多功能酶

Abstract:

The structure and properties of pepsin were summarized in this study. The enzyme system compositions of mammal and fish were concluded and the differences in these pepsins were presented. In addition, the newly founded activities of pepsin including digestion of guar galactomannan and nucleic acids were illustrated in details. As pepsin is the main digestive enzyme, the founding that pepsin is a "multifunctional enzyme". Based on the above, some suggestions were proposed for the future study and application of pepsins.

Key words: pepsin, enzyme system composition, new activities, multifunctional enzyme