生物学杂志
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摘要： 果蝇作为一种模式生物，在胚胎发育、疾病的发病机制以及基因表达调控等研究中发挥极其重要的作用。果蝇受到应激源刺激后，为维持身体内的稳态平衡，其体内细胞会发生一系列应激反应来应答。JNK信号通路在果蝇应激反应中起关键作用，结合最新研究进展，从JNK信号通路中相关蛋白的互作、负调控因子的调控、以及应激反应引起的JNK信号通路相关功能等方面进行综述。
关键词: 应激反应, JNK信号通路, 负调控因子
Abstract: As a model organism, fruit flies play an extremely important role in embryonic development, pathogenesis of diseases and regulation of gene expression. When the fruit flies are stimulated by stressors, the cells in the body respond to a series of stress responses to maintain homeostasis. JNK signaling pathway plays a key role in fruit flies stress reaction. In this paper, combining with the latest research progress of related protein interactions from the JNK signaling pathway and negative regulatory factors of regulation, the stress response caused by the JNK signaling pathway related function were summarized.
Key words: stress response, JNK signaling pathway, negative regulatory factor
中图分类号:
Q965.8
唐成晨, 贾佳. 果蝇JNK信号通路的研究进展[J]. 生物学杂志, doi: 10.3969/j.issn.2095-1736.2019.03.078.
TANG Cheng-chen， JIA Jia. The research progress in Drosophila JNK signaling pathway[J]. , doi: 10.3969/j.issn.2095-1736.2019.03.078.
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http://www.swxzz.com/CN/Y2019/V36/I3/78
